five prime therapeutics, inc

By tackling the tough scientific questions and untapped pathways, we aim to offer new hope by developing novel, breakthrough therapies that have potential to alter the course of disease in cancers with few treatment options. In addition, sales of our products are affected by pricing pressure, political and public scrutiny and reimbursement policies imposed by third-party payers, including governments, private insurance plans and managed care providers and may be affected by regulatory, clinical and guideline developments and domestic and international trends toward managed care and healthcare cost containment. Beam Therapeutics Inc's stock is NA in 2023, NA in the previous five trading days and down 38.44% in the past year. Clinical Trial Diversity and Representation, Clinical Trial Transparency, Data Sharing and Disclosure Practices, Adverse Event and Product Complaint Reporting, Environmental, Social & Governance Report 2021, Environment, Social and Governance Strategy, Community Investment and Amgen Foundation, Amgen To Acquire Five Prime Therapeutics For $1.9 Billion in Cash, https://investors.amgen.com/financials/sec-filings, https://investor.fiveprime.com/index.php/sec-filings, https://www.cancer.gov/about-cancer/treatment/drugs/stomach#1, http://www.prnewswire.com/news-releases/amgen-to-acquire-five-prime-therapeutics-for-1-9-billion-in-cash-301240358.html. The transaction is expected to close by the end of the second quarter and is subject to customary closing conditions, including the tender of at least a majority of the outstanding shares of Five Prime's common stock and the expiration or termination of the waiting period under the Hart-Scott-Rodino Antitrust Improvements Act of 1976. Amgen has completed its planned acquisition of Five Prime Therapeutics for $38.00 per share in cash, or approximately $1.9 billion. THOUSAND OAKS, Calif., April 16, 2021 /PRNewswire/ -- Amgen (NASDAQ:AMGN) today announced that it has successfully completed its previously announced tender offer to purchase all outstanding shares of common stock of Five Prime Therapeutics (NASDAQ:FPRX), a clinical-stage biotechnology company focused on developing immuno-oncology and targeted cancer therapies, for $38.00 per share in cash. Amgen. FivePrime is discovering and developing novel therapeutic proteins and antibodies by systematically screening all relevant proteins in the human body to find the best protein for treatment of a given clinical indication. Our results may be affected by our ability to successfully market both new and existing products domestically and internationally, clinical and regulatory developments involving current and future products, sales growth of recently launched products, competition from other products including biosimilars, difficulties or delays in manufacturing our products and global economic conditions. Currently, Beam Therapeutics Inc does not have a price-earnings ratio. An outbreak of disease or similar public health threat, such as COVID-19, and the public and governmental effort to mitigate against the spread of such disease, could have a significant adverse effect on the supply of materials for our manufacturing activities, the distribution of our products, the commercialization of our product candidates, and our clinical trial operations, and any such events may have a material adverse effect on our product development, product sales, business and results of operations. Our research drives us to understand the disease in the context of the patient's life not just their cancer journey so they can take control of their lives. Five Prime Therapeutics, Inc. Email Formats and Examples Enter employee name to find & verify emails, phones, social links, etc. Amgen to acquire Five Prime Therapeutics for $1.9 billion in cash. Prime Minister Fumio Kishida has repeatedly called for companies to increase wages, a plea that has gained urgency as prices have surged, leading to once-unthinkable increases in the cost of everything from food to . Forward-looking statements include, among other things, statements about the potential benefits of the proposed transaction; the prospective performance and outlook of Five Prime's business, performance and opportunities; any potential strategic benefits, synergies or opportunities expected as a result of the proposed transaction; the ability of the parties to complete the proposed transaction and the expected timing of completion of the proposed transaction; potential marketing or regulatory approvals for bemarituzumab, or potential future revenues from such product; as well as any assumptions underlying any of the foregoing. We perform a substantial amount of our commercial manufacturing activities at a few key facilities, including in Puerto Rico, and also depend on third parties for a portion of our manufacturing activities, and limits on supply may constrain sales of certain of our current products and product candidate development. [table] Ticker, No of HFs with positions, Total Value of HF Positions (x1000), Change in HF Position ESCA,3,5879,0 PLG,3,3650,0 HIL,10,26366,-3 MNTX,7,7980,1 Average,5.75,10969,-0.5 [/table]. In addition to DBL Investors, investors include Domain Associates, Versant Ventures, Kleiner Perkins Caufield and Byers, Texas Pacific Group, HealthCap, and Advanced Technology Ventures. Executive Director, Intellectual Property Five Prime Therapeutics, Inc. Jan 2017 - Aug 2018 1 year 8 . At Amgen, we are driven by our commitment to transform the lives of cancer patients and keep them at the center of everything we do. We develop product candidates internally and through licensing collaborations, partnerships and joint ventures. Peter H. Griffith, executive vice president and chief financial officer,DavidM. Reese, M.D., executive vice president of Research and Development, and Murdo Gordon, executive vice president of Global Commercial Operations at Amgen will participate. Disclosure: None. As a result, Amgen has accepted for payment all such validly tendered shares and will promptly (and in any event within two business days) pay for all such validly tendered shares. AccessedOctober 14, 2020. 1 five prime's lead candidate is bemarituzumab, a. Our efforts to collaborate with or acquire other companies, products or technology, and to integrate the operations of companies or to support the products or technology we have acquired, may not be successful. Global economic conditions may magnify certain risks that affect our business. Certain of our distributors, customers and payers have substantial purchasing leverage in their dealings with us. Amgen has completed its planned acquisition of Five Prime Therapeutics for $38.00 per share in cash, or approximately $1.9 billion.1 Five Prime's lead candidate is bemarituzumab, a first-in-class therapy that targets FGFR2b, which is overexpressed in approximately 30% of patients with HER2-negative gastric cancer, as well as in other solid tumors.2, Additionally, the FDA has granted bemarituzumab breakthrough therapy designation for patients with gastric or gastroesophageal junction (GEJ) cancer.3, Five Prime fits squarely within Amgen's leading oncology portfolio and includes bemarituzumab, a phase 3 trial-ready, first-in-class program for gastric cancer, the third leading cause of cancer mortality worldwide, Robert A. Bradway, chairman and chief executive officer at Amgen said in a press release. FIVE PRIME'S SHAREHOLDERS ARE ADVISED TO READ THE TENDER OFFER MATERIALS AND THE SOLICITATION/RECOMMENDATION STATEMENT, AS EACH MAY BE AMENDED OR SUPPLEMENTED FROM TIME TO TIME, AND ANY OTHER RELEVANT DOCUMENTS FILED BY FIVE PRIME OR AMGEN WITH THE SEC WHEN THEY BECOME AVAILABLE BEFORE THEY MAKE ANY DECISION WITH RESPECT TO THE TENDER OFFER. Find information to help you serve people who need medicine. Another agent in Five Primes pipeline is FPT155, a novel checkpoint inhibitor. This acquisition adds Five Prime's innovative pipeline to Amgen's leading oncology portfolio. At the data cutoff of May 2020, median PFS, which was the primary end point of the study, for patients treated with bemarituzumab/mFOLFOX6 (n = 77) was 9.5 months (95% CI, 7.3-12.9). Search / Go. Among these funds, Biotechnology Value Fund / BVF Inc held the most valuable stake in Five Prime Therapeutics Inc (NASDAQ:FPRX), which was worth $17.7 million at the end of the third quarter. Find More Contacts for Five Prime Therapeutics, Edit Lists Featuring This Company Section, Amgen Completes Five Prime Therapeutics Deal, Amgen completes $1.9B acquisition of Five Prime Therapeutics, Closed West Coast Biotechnology Companies, Harvard Medical School Alumni Founded Companies. Free and open company data on California (US) company FIVE PRIME THERAPEUTICS, INC. (company number 2375010), 111 OYSTER POINT BLVD SOUTH SAN FRANCISCO CA 94080 SaaS, Android, Cloud Computing, Medical Device), Where the organization is headquartered (e.g. Five Prime Therapeutics Revenue $13.2 M FY, 2020 Company summary Overview Five Prime Therapeutics is a biotechnology company focused on developing immuno-oncology and targeted cancer therapies. About Five Prime TherapeuticsFive Prime Therapeutics is a clinical stage biotechnology company relentlessly focused on rewriting cancer. About Gastric Cancer and GEJ CancerGastric cancer, also known as stomach cancer, is the third most common cause of cancer death worldwide and, excluding non-melanoma skin cancer, the fifth most common cancer worldwide, with over 1,000,000 new cases diagnosed each year.2 For HER2 negative patients, frontline therapy available today is the same systemic chemotherapy available since the 1990s.3,4. Video: Watch our video about the top 5 most popular hedge fund stocks. FivePrimes ProScreen Engine enables the rapid production and screening of all therapeutically. April 16, 2021. Five Prime Therapeutics, Inc., a clinical-stage biotechnology company, focuses on the discovery and development of protein therapeutics that block cancer and inflammatory disease processes. For the last four decades, we have been dedicated to discovering the firsts that matter in oncology and to finding ways to reduce the burden of cancer. The transaction is expected to close by the end of the second quarter and is subject to customary closing conditions, including the tender of at least a majority of the outstanding shares of Five Prime's common stock and the expiration or termination of the waiting period under the Hart-Scott-Rodino Antitrust Improvements Act of 1976. We leave no stone unturned when looking for the next great investment idea. Live audio of the conference call will be broadcast over the internet simultaneously and will be available to members of the news media, investors and the general public. Highlights from a week-long virtual event bringing Bloomberg Businessweek magazine to life. FivePrime is a clinical-stage biotechnology company that develops treatments for cancers. Following the completion of the tender offer, a wholly-owned subsidiary of Amgen will merge with Five Prime and shares of Five Prime that have not been tendered and purchased in the tender offer will be converted into the right to receive the same price per share in cash as paid in the tender offer (other than shares held by stockholders who properly demand and perfect appraisal rights under Delaware law). AmgenWebcast Investor CallAmgenwill host a webcast call for the investment community on Thursday, March 4, 2021, at10:30 a.m. EST. Five Prime's lead asset, bemarituzumab, is a first-in-class, Phase 3 ready anti-FGFR2b antibody with positive data from a randomized, placebo-controlled Phase 2 study in frontline advanced gastric or gastroesophageal junction(GEJ) cancer. This correlation suggests that FGFR2b could play a role in other epithelial cancers, including lung, breast, ovarian and other cancers. Amgen officials said they will continue to review additional Five Prime oncology agents. Of the 176 passengers on board, 138 were en route to Canada. About FGFR2bThe fibroblast growth factor (FGF)/fibroblast growth factor receptor (FGFR) pathway is implicated in the development and growth of cancer cells. Heading into the second quarter of 2020, a total of 16 of the hedge funds tracked by Insider Monkey were long this stock, a change of -16% from the fourth quarter of 2019. Hourly rate can vary widely depending on many important factors, including education, certifications, additional skills, the number of . It's worth mentioning that Minhua Zhang's Weld Capital Management said goodbye to the biggest position of the "upper crust" of funds followed by Insider Monkey, worth an estimated $0.1 million in stock. For more information, visitwww.amgen.comand follow us onwww.twitter.com/amgen. About FGFR2bThe fibroblast growth factor (FGF)/fibroblast growth factor receptor (FGFR) pathway is implicated in the development and growth of cancer cells. Our business performance could affect or limit the ability of our Board of Directors to declare a dividend or our ability to pay a dividend or repurchase our common stock. SOUTH SAN FRANCISCO, Calif., Jan. 29, 2018 (GLOBE NEWSWIRE) -- Five Prime Therapeutics, Inc. (Nasdaq:FPRX) announced today the closing of its upsized public offering of 5,897,435 shares of its common stock, which includes 769,230 shares sold upon the underwriters' full exercise of their option to purchase additional shares, resulting in aggregate gross proceeds of $115 million, before . The bemarituzumabPhase 2 FIGHT trial demonstrated clinically meaningful improvements in progression-free survival (PFS), overall survival (OS) and overall response rate (ORR) in the frontline treatment of patients with advanced gastric or GEJ cancer. Harri J Portrait Harri Jrvelinen SUZHOU, China, Jan. 09, 2023 (GLOBE NEWSWIRE) -- Ractigen Therapeutics, Inc. announced today that Dr. Harri Jrvelinen has been appointed Chief Operating Officer of the Company. relevant proteins in medically-focused assays at the highest quality standards in the industry. Food and Drug Administration. Furthermore, our research, testing, pricing, marketing and other operations are subject to extensive regulation by domestic and foreign government regulatory authorities. Five Prime Therapeutics Inc (NASDAQ: FPRX) has seen a decrease in activity from the world's largest hedge funds recently. Will continue to review additional Five Prime Therapeutics for $ 38.00 per share in cash, or approximately 1.9., additional skills, the number of agent in Five Primes pipeline FPT155... Customers and payers have substantial purchasing leverage in their dealings with us at10:30 a.m. EST 38.00... 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